Aseptika Ltd

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How it works 


 Step-by-step instructions - how the Aseptika Bioreactor Sampler works.  Download the Aseptika Bioreactor Sampler brochure or watch the video online at You Tube through this site.

 

 

  

 

 

 

 

 

Image showing the components of the Bioreactor Sampler. 


 

 

 
 
1. Connect to your bioreactor or fermentor using Luer-Lok® connectors

The Bioreactor Sampler is first connected to the bioreactor or fermentor using Luer-Lok® connectors, which are supplied as standard, or any other connector you specify (please contact us for details). Self adhesive Velcro straps are supplied so that the Bioreactor Sampler can be attached to any surface.
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2.  Connect to your bioreactor or fermentor using tube welders

The Bioreactor Sampler can also be connected to the bioreactor sample line using a tube welder. The Bioreactor Sampler has C-Flex tubing (20cm in length) for this purpose. You can specify other tubing as a bespoke version. Please contact us for details.
 
 
 
 
 
3.  Flushing the sampling line

A Unique unidirectional flow system ensures that fresh sample is flushed through the sampling lines for each sample collected preventing sample returning to the bioreactor or fermentor vessel. By preventing back-flow, contamination is eliminated.
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4.  Expelling flushed sample to waste

Fresh sample is used to flush the manifold and is expelled into the 1L waste bag via a second non-return valve, which stops any back-flow into the device from the waste bag.  At no time is sample exposed to the atmosphere or the operator exposed to the sample.
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5.  Accessing the Sampling Syringe - the SNAP-FLOWTM valve (SNAP)

Each sample is taken into its own, use-once syringe, via a SNAP-FLOWTM valve which is only opened by bending the plastic housing to snap and break this single-use valve.  This protects the Sample Syringe from previous samples.
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6. Filling the Sampling Syringe (SAMPLE)
Each sample is taken into its own, use-once syringe, via a SNAP-FLOWTM valve which is only opened by bending the plastic housing to snap and break this single-use valve. 
 
 
 
 
 
 
 
7. Sealing the sample into the Sample Syringe using the Aseptika Tube Sealer (SEAL)

Once the sample has been collected into the Sampling Syring, the Aseptika Tube SealerTM is used to seal the tubing betweem the SNAP-FLOWTM valve and the Sample Syringe.  This takes just 2-3 seconds.
 
 
 
 
 
 
 
 
 
 
 
 
7. Sealing and cutting the Sample Syringe from the Bioreactor Sampler

The sealed tubing can then be gently separated, leaving a clean and drip-free tube end.